“Heart attacks are still the main causes of death throughout the world, who often come with awesome complications,” said Zhong Wang, Ph.D., a Professor of Heart Operations at the University of Michigan Frankel Cardiovascular, which is a senior writer of learning.
Medium chain fatty acids found in energy drinks may be a one-day assistance to protect against a heart attack injury, suggesting a recent study by researchers at the University of Michigan Frankel Cardiovascular Center.
Preclinist studies are published in ‘Elife’.
“Heart attacks are still the main causes of death throughout the world, who often come with awesome complications,” said Zhong Wang, Ph.D., a Professor of Heart Operations at the University of Michigan Frankel Cardiovascular, which is a senior writer of learning.
He added, “Better choices are needed to reduce injury to the heart after a heart attack, and even improve heart function. In this publication, we target the interaction between energy and epigenetic metabolism mediated by 8C medium chain fatty acids.”
Wang and colleagues can protect from a heart attack injury on mouse models with octanoic acid, medium-carbon medium chain fatty acids (8C), and some other metabolites. The fatty acid produces acetyl-coa, building blocks for energy metabolism, which is very necessary to stressful hearts
The idea is that a doctor will give this therapy to someone once they arrive at the hospital after experiencing a heart attack, to reduce further injury and improve heart function during recovery, he said.
“Understanding the crosstalk between energy and epigenetic metabolism may not only provide an effective target for myocardial infarction, but also has a broad implication in damage to other ischemic organs caused by organ damage outside of heart disease,” said Ienglam Lei, Phart., From the Frankel Department CVC heart surgery and Macau University in China, who conducted the main research experiment.
Wang said the next step was to test this molecule in a large animal model, followed by clinical trials. The research team has studied epigenetic regulation of a heart attack for more than 10 years.